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A metabolomic strategy defines the regulation of lipid content and global metabolism by Δ9 desaturases in Caenorhabditis elegans

BACKGROUND: Caenorhabditis elegans provides a genetically tractable model organism to investigate the network of genes involved in fat metabolism and how regulation is perturbed to produce the complex phenotype of obesity. C. elegans possess the full range of desaturases, including the Δ9 desaturase...

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Detalles Bibliográficos
Autores principales: Castro, Cecilia, Sar, Funda, Shaw, W Robert, Mishima, Masanori, Miska, Eric A, Griffin, Julian L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398271/
https://www.ncbi.nlm.nih.gov/pubmed/22264337
http://dx.doi.org/10.1186/1471-2164-13-36