Cargando…

A metabolomic strategy defines the regulation of lipid content and global metabolism by Δ9 desaturases in Caenorhabditis elegans

BACKGROUND: Caenorhabditis elegans provides a genetically tractable model organism to investigate the network of genes involved in fat metabolism and how regulation is perturbed to produce the complex phenotype of obesity. C. elegans possess the full range of desaturases, including the Δ9 desaturase...

Descripción completa

Detalles Bibliográficos
Autores principales:	Castro, Cecilia, Sar, Funda, Shaw, W Robert, Mishima, Masanori, Miska, Eric A, Griffin, Julian L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398271/ https://www.ncbi.nlm.nih.gov/pubmed/22264337 http://dx.doi.org/10.1186/1471-2164-13-36

Ejemplares similares

DAF-16 and Δ(9) Desaturase Genes Promote Cold Tolerance in Long-Lived Caenorhabditis elegans age-1 Mutants
por: Savory, Fiona R., et al.
Publicado: (2011)

Juniperonic Acid Biosynthesis is Essential in Caenorhabditis elegans Lacking Δ6 Desaturase (fat-3) and Generates New ω-3 Endocannabinoids
por: Guha, Sujay, et al.
Publicado: (2020)

Caenorhabditis elegans and friends in Los Angeles
por: Alvarez-Saavedra, Ezequiel A, et al.
Publicado: (2005)

Chemically defined medium and Caenorhabditis elegans
por: Szewczyk, Nathaniel J, et al.
Publicado: (2003)

Canalisation and plasticity on the developmental manifold of Caenorhabditis elegans
por: Jordan, David J, et al.
Publicado: (2023)

Defining the Response of Caenorhabditis elegans to Multiple Simultaneous Stressors
por: Sutphin, George, et al.
Publicado: (2020)

Regulation of fatty acid desaturase- and immunity gene-expression by mbk-1/DYRK1A in Caenorhabditis elegans
por: Mack, Hildegard I. D., et al.
Publicado: (2022)

Dopamine Signaling Regulates Fat Content through β-Oxidation in Caenorhabditis elegans
por: Barros, Alexandre Guimarães de Almeida, et al.
Publicado: (2014)

Metabolomic signature associated with reproduction-regulated aging in Caenorhabditis elegans
por: Wan, Qin-Li, et al.
Publicado: (2017)

An Alternative STAT Signaling Pathway Acts in Viral Immunity in Caenorhabditis elegans
por: Tanguy, Mélanie, et al.
Publicado: (2017)

Caenorhabditis elegans comes of age
por: Ceron, Julian, et al.
Publicado: (2008)

Acyl-Lipid Δ(6)-Desaturase May Act as a First FAD in Cyanobacteria
por: Starikov, Alexander Y., et al.
Publicado: (2022)

Growth of Caenorhabditis elegans in Defined Media Is Dependent on Presence of Particulate Matter
por: Flavel, Matthew R., et al.
Publicado: (2017)

Single-Copy Knock-In Loci for Defined Gene Expression in Caenorhabditis elegans
por: Silva-García, Carlos G., et al.
Publicado: (2019)

Identification and characterization of new Δ-17 fatty acid desaturases
por: Xue, Zhixiong, et al.
Publicado: (2012)

Caenorhabditis elegans for research on cancer hallmarks
por: Cerón, Julián
Publicado: (2023)

Metabolomics and lipidomics in Caenorhabditis elegans using a single-sample preparation
por: Molenaars, Marte, et al.
Publicado: (2021)

Caenorhabditis Elegans
Publicado: (2000)

Functional Desaturase Fads1 (Δ5) and Fads2 (Δ6) Orthologues Evolved before the Origin of Jawed Vertebrates
por: Castro, Luís Filipe Costa, et al.
Publicado: (2012)

Analysis of Caenorhabditis elegans Sperm Number, Size, Activation, and Mitochondrial Content
por: Hammerquist, Amy M., et al.
Publicado: (2021)

Antiviral RNA Interference against Orsay Virus Is neither Systemic nor Transgenerational in Caenorhabditis elegans
por: Ashe, Alyson, et al.
Publicado: (2015)

Capillary electrophoresis-mass spectrometry as a tool for Caenorhabditis elegans metabolomics research
por: Salzer, Liesa, et al.
Publicado: (2023)

Identification of putative reader proteins of 5-methylcytosine and its derivatives in Caenorhabditis elegans RNA
por: Navarro, IC, et al.
Publicado: (2022)

Application of Caenorhabditis elegans in Lipid Metabolism Research
por: An, Lu, et al.
Publicado: (2023)

Competition between virus-derived and endogenous small RNAs regulates gene expression in Caenorhabditis elegans
por: Sarkies, Peter, et al.
Publicado: (2013)

Towards generalization for Caenorhabditis elegans detection
por: Escobar-Benavides, Santiago, et al.
Publicado: (2023)

Most Caenorhabditis elegans microRNAs Are Individually Not Essential for Development or Viability
por: Miska, Eric A, et al.
Publicado: (2007)

The Nucleolus of Caenorhabditis elegans
por: Lee, Li-Wei, et al.
Publicado: (2012)

Immunometabolism in Caenorhabditis elegans
por: Anderson, Sarah M., et al.
Publicado: (2020)

Immunosenescence in Caenorhabditis elegans
por: Kim, Sieun S., et al.
Publicado: (2022)

Oogenesis in Caenorhabditis elegans
por: Davis, Gregory M., et al.
Publicado: (2023)

High-content behavioral analysis of Caenorhabditis elegans in precise spatiotemporal chemical environments
por: Albrecht, Dirk R, et al.
Publicado: (2011)

Tung tree stearoyl‐acyl carrier protein Δ9 desaturase improves oil content and cold resistance of Arabidopsis and Saccharomyces cerevisiae
por: Chen, Junjie, et al.
Publicado: (2023)

Δ12-Fatty Acid Desaturase from Candida parapsilosis Is a Multifunctional Desaturase Producing a Range of Polyunsaturated and Hydroxylated Fatty Acids
por: Buček, Aleš, et al.
Publicado: (2014)

Translational adaptation to heat stress is mediated by RNA 5‐methylcytosine in Caenorhabditis elegans
por: Navarro, Isabela Cunha, et al.
Publicado: (2020)

The microRNA miR-124 controls gene expression in the sensory nervous system of Caenorhabditis elegans
por: Clark, Alejandra M., et al.
Publicado: (2010)

Function and Regulation of Lipid Biology in Caenorhabditis elegans Aging
por: Hou, Nicole Shangming, et al.
Publicado: (2012)

Nuclear lipid droplets and nuclear damage in Caenorhabditis elegans
por: Mosquera, Jose Verdezoto, et al.
Publicado: (2021)

Identification and functional analysis of the genes encoding Δ(6)-desaturase from Ribes nigrum†
por: Song, Li-Ying, et al.
Publicado: (2010)

Purification and function analysis of the Δ-17 fatty acid desaturase with or without transmembrane domain
por: Zhou, Haoyu, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_vkvghd1ksra34t97krqiirtb7e