Validation of an LC-MS/MS method to determine five immunosuppressants with deuterated internal standards including MPA

BACKGROUND: Therapeutic drug monitoring of immunosuppressive drugs in organ-transplanted patients is crucial to prevent intoxication or transplant rejection due to inadequate dosage. The commonly used immunoassays have been gradually undergoing replacement by mass spectrometry, since this physical m...

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Detalles Bibliográficos
Autores principales: Buchwald, Armin, Winkler, Karl, Epting, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Technical Advance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398287/
https://www.ncbi.nlm.nih.gov/pubmed/22236286
http://dx.doi.org/10.1186/1472-6904-12-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398287/
https://www.ncbi.nlm.nih.gov/pubmed/22236286
http://dx.doi.org/10.1186/1472-6904-12-2

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