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Validation of an LC-MS/MS method to determine five immunosuppressants with deuterated internal standards including MPA

BACKGROUND: Therapeutic drug monitoring of immunosuppressive drugs in organ-transplanted patients is crucial to prevent intoxication or transplant rejection due to inadequate dosage. The commonly used immunoassays have been gradually undergoing replacement by mass spectrometry, since this physical m...

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Detalles Bibliográficos
Autores principales:	Buchwald, Armin, Winkler, Karl, Epting, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Technical Advance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398287/ https://www.ncbi.nlm.nih.gov/pubmed/22236286 http://dx.doi.org/10.1186/1472-6904-12-2

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