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Localized Netrins Act as Positional Cues to Control Layer-Specific Targeting of Photoreceptor Axons in Drosophila

A shared feature of many neural circuits is their organization into synaptic layers. However, the mechanisms that direct neurites to distinct layers remain poorly understood. We identified a central role for Netrins and their receptor Frazzled in mediating layer-specific axon targeting in the Drosop...

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Detalles Bibliográficos
Autores principales: Timofeev, Katarina, Joly, Willy, Hadjieconomou, Dafni, Salecker, Iris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398394/
https://www.ncbi.nlm.nih.gov/pubmed/22794263
http://dx.doi.org/10.1016/j.neuron.2012.04.037