Molecular Chaperones as Targets to Circumvent the CFTR Defect in Cystic Fibrosis

Cystic Fibrosis (CF) is the most common autosomal recessive lethal disorder among Caucasian populations. CF results from mutations and resulting dysfunction of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR). CFTR is a cyclic AMP-dependent chloride channel that is localized to the api...

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Detalles Bibliográficos
Autores principales: Chanoux, Rebecca A., Rubenstein, Ronald C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398409/
https://www.ncbi.nlm.nih.gov/pubmed/22822398
http://dx.doi.org/10.3389/fphar.2012.00137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398409/
https://www.ncbi.nlm.nih.gov/pubmed/22822398
http://dx.doi.org/10.3389/fphar.2012.00137

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