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The Promyelocytic Leukemia Zinc Finger Protein: Two Decades of Molecular Oncology

The promyelocytic leukemia zinc finger (PLZF) protein, also known as Zbtb16 or Zfp145, was first identified in a patient with acute promyelocytic leukemia, where a reciprocal chromosomal translocation t(11;17)(q23;q21) resulted in a fusion with the RARA gene encoding retinoic acid receptor alpha. Th...

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Detalles Bibliográficos
Autores principales: Suliman, Bandar Ali, Xu, Dakang, Williams, Bryan Raymond George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398472/
https://www.ncbi.nlm.nih.gov/pubmed/22822476
http://dx.doi.org/10.3389/fonc.2012.00074