The deubiquitinylation and localization of PTEN are regulated by a HAUSP–PML network

Nuclear exclusion of the PTEN tumour suppressor has been associated with cancer progression(1-6). However, the mechanisms leading to this aberrant PTEN localization in human cancers are currently unknown. We have previously reported that ubiquitinylation of PTEN at specific lysine residues regulates...

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Detalles Bibliográficos
Autores principales: Song, Min Sup, Salmena, Leonardo, Carracedo, Arkaitz, Egia, Ainara, Lo-Coco, Francesco, Teruya-Feldstein, Julie, Pandolfi, Pier Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398484/
https://www.ncbi.nlm.nih.gov/pubmed/18716620
http://dx.doi.org/10.1038/nature07290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398484/
https://www.ncbi.nlm.nih.gov/pubmed/18716620
http://dx.doi.org/10.1038/nature07290

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