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Modified Lipooligosaccharide Structure Protects Nontypeable Haemophilus influenzae from IgM-Mediated Complement Killing in Experimental Otitis Media

Nontypeable Haemophilus influenzae (NTHi) is a Gram-negative, human-restricted pathogen. Although this bacterium typically colonizes the nasopharynx in the absence of clinical symptoms, it is also one of the major pathogens causing otitis media (OM) in children. Complement represents an important as...

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Detalles Bibliográficos
Autores principales: Langereis, Jeroen D., Stol, Kim, Schweda, Elke K., Twelkmeyer, Brigitte, Bootsma, Hester J., de Vries, Stefan P. W., Burghout, Peter, Diavatopoulos, Dimitri A., Hermans, Peter W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398534/
https://www.ncbi.nlm.nih.gov/pubmed/22761391
http://dx.doi.org/10.1128/mBio.00079-12