Increased Cell-Matrix Adhesion upon Constitutive Activation of Rho Proteins by Cytotoxic Necrotizing Factors from E. Coli and Y. Pseudotuberculosis

Cytotoxic necrotizing factors (CNFs) encompass a class of autotransporter toxins produced by uropathogenic E. coli (CNF1) or Y. pseudotuberculosis (CNFy). CNF toxins deamidate and thereby constitutively activate RhoA, Rac1, and Cdc42. In this study, the effects of CNF1 on cell-matrix adhesion are an...

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Detalles Bibliográficos
Autores principales: May, Martin, Kolbe, Tanja, Wang, Tianbang, Schmidt, Gudula, Genth, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398657/
https://www.ncbi.nlm.nih.gov/pubmed/22830013
http://dx.doi.org/10.1155/2012/570183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398657/
https://www.ncbi.nlm.nih.gov/pubmed/22830013
http://dx.doi.org/10.1155/2012/570183

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