The Transcriptional and Epigenomic Foundations of Ground State Pluripotency

Mouse embryonic stem (ES) cells grown in serum exhibit greater heterogeneity in morphology and expression of pluripotency factors than ES cells cultured in defined medium with inhibitors of two kinases (Mek and GSK3), a condition known as “2i” postulated to establish a naive ground state. We show th...

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Detalles Bibliográficos
Autores principales: Marks, Hendrik, Kalkan, Tüzer, Menafra, Roberta, Denissov, Sergey, Jones, Kenneth, Hofemeister, Helmut, Nichols, Jennifer, Kranz, Andrea, Francis Stewart, A., Smith, Austin, Stunnenberg, Hendrik G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398752/
https://www.ncbi.nlm.nih.gov/pubmed/22541430
http://dx.doi.org/10.1016/j.cell.2012.03.026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398752/
https://www.ncbi.nlm.nih.gov/pubmed/22541430
http://dx.doi.org/10.1016/j.cell.2012.03.026

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