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Homology modelling of CB1 receptor and selection of potential inhibitor against Obesity

Obesity and patient morbidity has become a health concern worldwide. Obesity is associated with over activity of the endocannabinoid system, which is involved in the regulation of appetite, lipogenesis and insulin resistance. Hypothalamic cannabinoid-1 receptor (CB1R) inverse agonists reduce body we...

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Detalles Bibliográficos
Autores principales: Shrinivasan, Mahesh, Skariyachan, Sinosh, Aparna, Vaka, Kolte, Vinod Rama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398776/
https://www.ncbi.nlm.nih.gov/pubmed/22829723
http://dx.doi.org/10.6026/97320630008523