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Apolipoprotein E COG 133 mimetic peptide improves 5-fluorouracil-induced intestinal mucositis

BACKGROUND: Intestinal mucositis is one of the major troublesome side effects of anticancer chemotherapy leading to poor patient compliance. In this study we addressed the role of the novel apolipoprotein E (ApoE) COG 133 mimetic peptide in 5-fluorouracil (5-FU)-challenged Swiss mice and IEC-6 cell...

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Detalles Bibliográficos
Autores principales: Azevedo, Orleâncio Gomes R, Oliveira, Renato André C, Oliveira, Bruna Castro, Zaja-Milatovic, Snjezana, Araújo, Celina Viana, Wong, Deysi Viviana T, Costa, Tiê Bezerra, Lucena, Herene Barros Miranda, Lima-Júnior, Roberto César P, Ribeiro, Ronaldo A, Warren, Cirle A, Lima, Aldo Ângelo M, Vitek, Michael P, Guerrant, Richard L, Oriá, Reinaldo B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398852/
https://www.ncbi.nlm.nih.gov/pubmed/22524518
http://dx.doi.org/10.1186/1471-230X-12-35