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Mesenchymal Stromal Cells but Not Cardiac Fibroblasts Exert Beneficial Systemic Immunomodulatory Effects in Experimental Myocarditis

Systemic application of mesenchymal stromal cells (MSCs) in inflammatory cardiomyopathy exerts cardiobeneficial effects. The mode of action is unclear since a sufficient and long-acting cardiac homing of MSCs is unlikely. We therefore investigated the regulation of the immune response in coxsackievi...

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Detalles Bibliográficos
Autores principales: Savvatis, Konstantinos, van Linthout, Sophie, Miteva, Kapka, Pappritz, Kathleen, Westermann, Dirk, Schefold, Joerg C., Fusch, Gerhard, Weithäuser, Alice, Rauch, Ursula, Becher, Peter-Moritz, Klingel, Karin, Ringe, Jochen, Kurtz, Andreas, Schultheiss, Heinz-Peter, Tschöpe, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398879/
https://www.ncbi.nlm.nih.gov/pubmed/22815907
http://dx.doi.org/10.1371/journal.pone.0041047