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Activation of P2X7 Promotes Cerebral Edema and Neurological Injury after Traumatic Brain Injury in Mice

Traumatic brain injury (TBI) is a leading cause of death and disability worldwide. Cerebral edema, the abnormal accumulation of fluid within the brain parenchyma, contributes to elevated intracranial pressure (ICP) and is a common life-threatening neurological complication following TBI. Unfortunate...

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Detalles Bibliográficos
Autores principales: Kimbler, Donald E., Shields, Jessica, Yanasak, Nathan, Vender, John R., Dhandapani, Krishnan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398891/
https://www.ncbi.nlm.nih.gov/pubmed/22815977
http://dx.doi.org/10.1371/journal.pone.0041229