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Distribution and Radiosensitizing Effect of Cholesterol-Coupled Dbait Molecule in Rat Model of Glioblastoma

BACKGROUND: Glioma is the most aggressive tumor of the brain and the most efficient treatments are based on radiotherapy. However, tumors are often resistant to radiotherapy due to an enhanced DNA repair activity. Short and stabilized DNA molecules (Dbait) have recently been proposed as an efficient...

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Detalles Bibliográficos
Autores principales: Coquery, Nicolas, Pannetier, Nicolas, Farion, Régine, Herbette, Aurélie, Azurmendi, Leire, Clarencon, Didier, Bauge, Stéphane, Josserand, Véronique, Rome, Claire, Coll, Jean-Luc, Sun, Jian-Sheng, Barbier, Emmanuel L., Dutreix, Marie, Remy, Chantal C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398898/
https://www.ncbi.nlm.nih.gov/pubmed/22815765
http://dx.doi.org/10.1371/journal.pone.0040567