Divergence of Rho residue 43 impacts GEF activity

RhoA, RhoB and RhoC GTPases are over 85% identical at the amino acid level, with RhoA and RhoC differing at only one residue (43) across the initial two-thirds of their sequences. A putative regulatory distinction between the molecules is their capacity to be uniquely activated by guanine nucleotide...

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Detalles Bibliográficos
Autores principales: Sloan, Christina M., Quinn, Clancy V., Peters, Justin P., Farley, Janean, Goetzinger, Chris, Wernli, Molly, DeMali, Kris A., Ellerbroek, Shawn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398911/
https://www.ncbi.nlm.nih.gov/pubmed/22673745
http://dx.doi.org/10.4161/sgtp.19557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398911/
https://www.ncbi.nlm.nih.gov/pubmed/22673745
http://dx.doi.org/10.4161/sgtp.19557

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