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KRAS mutant colorectal tumors: Past and present

The treatment of metastatic colorectal cancer (mCRC) remains one of the largest hurdles in cancer therapeutics to date. The most advanced treatment option for mCRC patients are anti-epidermal growth factor receptor (EGFR) monoclonal antibodies (mAbs) that bind to and inhibit the activity of EGFR. Wh...

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Detalles Bibliográficos
Autores principales: Brand, Toni M., Wheeler, Deric L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398915/
https://www.ncbi.nlm.nih.gov/pubmed/22714415
http://dx.doi.org/10.4161/sgtp.18751