Rac-ing to the plasma membrane: The long and complex work commute of Rac1 during cell signaling

The functional cycle of the Rac1 GTPase involves a large number of steps, including post-translational processing, cytosolic sequestration by RhoGDIs, translocation to specific subcellular localizations, activation by GDP/GTP exchange, inactivation by GTP hydrolysis, and re-formation of cytosolic Ra...

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Detalles Bibliográficos
Autores principales: Bustelo, Xosé R., Ojeda, Virginia, Barreira, María, Sauzeau, Vincent, Castro-Castro, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398920/
https://www.ncbi.nlm.nih.gov/pubmed/22714419
http://dx.doi.org/10.4161/sgtp.19111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398920/
https://www.ncbi.nlm.nih.gov/pubmed/22714419
http://dx.doi.org/10.4161/sgtp.19111

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