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Reduced Retinal Microvascular Density, Improved Forepaw Reach, Comparative Microarray and Gene Set Enrichment Analysis with c-jun Targeting DNA Enzyme

Retinal neovascularization is a critical component in the pathogenesis of common ocular disorders that cause blindness, and treatment options are limited. We evaluated the therapeutic effect of a DNA enzyme targeting c-jun mRNA in mice with pre-existing retinal neovascularization. A single injection...

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Detalles Bibliográficos
Autores principales: Chan, Cecilia W. S., Kaplan, Warren, Parish, Christopher R., Khachigian, Levon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398922/
https://www.ncbi.nlm.nih.gov/pubmed/22815700
http://dx.doi.org/10.1371/journal.pone.0039160