Primary Vaccination with Low Dose Live Dengue 1 Virus Generates a Proinflammatory, Multifunctional T Cell Response in Humans

The four dengue virus serotypes (DENV-1–DENV-4) have a large impact on global health, causing 50–100 million cases of dengue fever annually. Herein, we describe the first kinetic T cell response to a low-dose DENV-1 vaccination study (10 PFU) in humans. Using flow cytometry, we found that proinflamm...

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Detalles Bibliográficos
Autores principales: Lindow, Janet C., Borochoff-Porte, Nathan, Durbin, Anna P., Whitehead, Stephen S., Fimlaid, Kelly A., Bunn, Janice Y., Kirkpatrick, Beth D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398956/
https://www.ncbi.nlm.nih.gov/pubmed/22816004
http://dx.doi.org/10.1371/journal.pntd.0001742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398956/
https://www.ncbi.nlm.nih.gov/pubmed/22816004
http://dx.doi.org/10.1371/journal.pntd.0001742

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