Stochastic Model of In-Vivo X4 Emergence during HIV Infection: Implications for the CCR5 Inhibitor Maraviroc

The emergence of X4 tropic viral strains throughout the course of HIV infection is associated with poorer prognostic outcomes and faster progressions to AIDS than for patients in whom R5 viral strains predominate. Here we investigate a stochastic model to account for the emergence of X4 virus via mu...

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Detalles Bibliográficos
Autores principales: Savkovic, Borislav, Symonds, Geoff, Murray, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398969/
https://www.ncbi.nlm.nih.gov/pubmed/22866173
http://dx.doi.org/10.1371/journal.pone.0038755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398969/
https://www.ncbi.nlm.nih.gov/pubmed/22866173
http://dx.doi.org/10.1371/journal.pone.0038755

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