Transport of Fibroblast Growth Factor 2 in the Pericellular Matrix Is Controlled by the Spatial Distribution of Its Binding Sites in Heparan Sulfate

The heparan sulfate (HS) chains of proteoglycans are a key regulatory component of the extracellular matrices of animal cells, including the pericellular matrix around the plasma membrane. In these matrices they regulate transport, gradient formation, and effector functions of over 400 proteins cent...

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Detalles Bibliográficos
Autores principales: Duchesne, Laurence, Octeau, Vivien, Bearon, Rachel N., Beckett, Alison, Prior, Ian A., Lounis, Brahim, Fernig, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398970/
https://www.ncbi.nlm.nih.gov/pubmed/22815649
http://dx.doi.org/10.1371/journal.pbio.1001361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398970/
https://www.ncbi.nlm.nih.gov/pubmed/22815649
http://dx.doi.org/10.1371/journal.pbio.1001361

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