DMSO is a strong inducer of DNA hydroxymethylation in pre-osteoblastic MC3T3-E1 cells

Artificial induction of active DNA demethylation appears to be a possible and useful strategy in molecular biology research and therapy development. Dimethyl sulfoxide (DMSO) was shown to cause phenotypic changes in embryonic stem cells altering the genome-wide DNA methylation profiles. Here we repo...

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Detalles Bibliográficos
Autores principales: Thaler, Roman, Spitzer, Silvia, Karlic, Heidrun, Klaushofer, Klaus, Varga, Franz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398991/
https://www.ncbi.nlm.nih.gov/pubmed/22507896
http://dx.doi.org/10.4161/epi.20163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398991/
https://www.ncbi.nlm.nih.gov/pubmed/22507896
http://dx.doi.org/10.4161/epi.20163

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