Different measures of “genome-wide” DNA methylation exhibit unique properties in placental and somatic tissues

DNA methylation of CpGs located in two types of repetitive elements—LINE1 (L1) and Alu—is used to assess “global” changes in DNA methylation in studies of human disease and environmental exposure. L1 and Alu contribute close to 30% of all base pairs in the human genome and transposition of repetitiv...

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Detalles Bibliográficos
Autores principales: Price, E. Magda, Cotton, Allison M., Peñaherrera, Maria S., McFadden, Deborah E., Kobor, Michael S., Robinson, Wendy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398992/
https://www.ncbi.nlm.nih.gov/pubmed/22531475
http://dx.doi.org/10.4161/epi.20221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398992/
https://www.ncbi.nlm.nih.gov/pubmed/22531475
http://dx.doi.org/10.4161/epi.20221

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