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Ultraviolet Shadowing of RNA Can Cause Significant Chemical Damage in Seconds
Chemical purity of RNA samples is important for high-precision studies of RNA folding and catalytic behavior, but photodamage accrued during ultraviolet (UV) shadowing steps of sample preparation can reduce this purity. Here, we report the quantitation of UV-induced damage by using reverse transcrip...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399121/ https://www.ncbi.nlm.nih.gov/pubmed/22816040 http://dx.doi.org/10.1038/srep00517 |