18α-Glycyrrhetinic Acid Down-Regulates Expression of Type I and III Collagen via TGF-Β1/Smad Signaling Pathway in Human and Rat Hepatic Stellate Cells

Objective: To investigate the effects of 18α-glycyrrhetinic acid (18α-GA) on the expression of type I and III collagen in human and rat hepatic stellate cells (HSC) and to explore the role of TGF-β1/Smad signaling pathway involved. Methods: Following 18α-GA treatment, the cell viability and cell gro...

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Detalles Bibliográficos
Autores principales: Zong, Lei, Qu, Ying, Xu, Ming-yi, Dong, Yu-wei, Lu, Lun-gen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2012
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399217/
https://www.ncbi.nlm.nih.gov/pubmed/22811611
http://dx.doi.org/10.7150/ijms.4395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399217/
https://www.ncbi.nlm.nih.gov/pubmed/22811611
http://dx.doi.org/10.7150/ijms.4395

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