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Deciphering the Role of Insulin-Like Growth Factor-I Receptor in Trastuzumab Resistance

Resistance to the HER2-targeted antibody trastuzumab is a major clinical concern in the treatment of HER2-overexpressing metastatic breast cancer. Increased expression or signaling of the insulin-like growth factor-I receptor (IGF-IR) has been reported in a subset of cell lines and clinical samples...

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Detalles Bibliográficos
Autor principal:	Nahta, Rita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399380/ https://www.ncbi.nlm.nih.gov/pubmed/22830017 http://dx.doi.org/10.1155/2012/648965

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