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The role of Bax and caspase-3 in doppel-induced apoptosis of cerebellar granule cells
Doppel (Dpl) protein is a paralog of the prion protein (PrP) that shares 25% sequence similarity with the C-terminus of PrP, a common N-glycosylation site and a C-terminal signal peptide for attachment of a glycosylphophatidyl inositol anchor. Whereas PrP(C) is highly expressed in the central nervou...
Autores principales: | Didonna, Alessandro, Sussman, Joshua, Benetti, Federico, Legname, Giuseppe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399532/ https://www.ncbi.nlm.nih.gov/pubmed/22561161 http://dx.doi.org/10.4161/pri.20026 |
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