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Simple F Test Reveals Gene-Gene Interactions in Case-Control Studies

Missing heritability is still a challenge for Genome Wide Association Studies (GWAS). Gene-gene interactions may partially explain this residual genetic influence and contribute broadly to complex disease. To analyze the gene-gene interactions in case-control studies of complex disease, we propose a...

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Detalles Bibliográficos
Autores principales: Chen, Guanjie, Yuan, Ao, Zhou, Jie, Bentley, Amy R., Adeyemo, Adebowale, Rotimi, Charles N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399554/
https://www.ncbi.nlm.nih.gov/pubmed/22837643
http://dx.doi.org/10.4137/BBI.S9867