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Pak1 Regulates the Orientation of Apical Polarization and Lumen Formation by Distinct Pathways
The development of the basic architecture of branching tubules enclosing a central lumen that characterizes most epithelial organs crucially depends on the apico-basolateral polarization of epithelial cells. Signals from the extracellular matrix control the orientation of the apical surface, so that...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399788/ https://www.ncbi.nlm.nih.gov/pubmed/22815903 http://dx.doi.org/10.1371/journal.pone.0041039 |