Recombinant Lipidated HPV E7 Induces a Th-1-Biased Immune Response and Protective Immunity against Cervical Cancer in a Mouse Model

The E7 oncoprotein of human papillomavirus (HPV) is an ideal target for developing immunotherapeutic strategies against HPV-associated tumors. However, because protein-based immunogens alone are poor elicitors of the cytotoxic T-lymphocyte (CTL) responses, they have been difficult to exploit for the...

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Detalles Bibliográficos
Autores principales: Huang, Chiung-Yi, Chen, Jeremy J. W., Shen, Kuan-Yin, Chang, Li-Sheng, Yeh, Yi-Chen, Chen, I-Hua, Chong, Pele, Liu, Shih-Jen, Leng, Chih-Hsiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399806/
https://www.ncbi.nlm.nih.gov/pubmed/22815882
http://dx.doi.org/10.1371/journal.pone.0040970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399806/
https://www.ncbi.nlm.nih.gov/pubmed/22815882
http://dx.doi.org/10.1371/journal.pone.0040970

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