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Prostate Specific Membrane Antigen (PSMA) Regulates Angiogenesis Independently of VEGF during Ocular Neovascularization

BACKGROUND: Aberrant growth of blood vessels in the eye forms the basis of many incapacitating diseases and currently the majority of patients respond to anti-angiogenic therapies based on blocking the principal angiogenic growth factor, vascular endothelial growth factor (VEGF). While highly succes...

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Detalles Bibliográficos
Autores principales: Grant, Christina L., Caromile, Leslie A., Durrani, Khayyam, Rahman, M. Mamunur, Claffey, Kevin P., Fong, Guo-Hua, Shapiro, Linda H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399825/
https://www.ncbi.nlm.nih.gov/pubmed/22815987
http://dx.doi.org/10.1371/journal.pone.0041285