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Structural Differences between Human Proteins and Aero- and Microbial Allergens Define Allergenicity

The current paradigm suggests that structural homology of allergenic proteins to microbial (particularly helminths) or human proteins underlie their allergenic nature. To examine systematically the structural relationships among allergens and proteins of pathogens (helminths, protozoans, fungi and b...

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Detalles Bibliográficos
Autores principales: Santiago, Helton da Costa, Bennuru, Sasisekhar, Ribeiro, José M. C., Nutman, Thomas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399830/
https://www.ncbi.nlm.nih.gov/pubmed/22815762
http://dx.doi.org/10.1371/journal.pone.0040552