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Loop 7 of E2 Enzymes: An Ancestral Conserved Functional Motif Involved in the E2-Mediated Steps of the Ubiquitination Cascade

The ubiquitin (Ub) system controls almost every aspect of eukaryotic cell biology. Protein ubiquitination depends on the sequential action of three classes of enzymes (E1, E2 and E3). E2 Ub-conjugating enzymes have a central role in the ubiquitination pathway, interacting with both E1 and E3, and in...

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Detalles Bibliográficos
Autores principales: Papaleo, Elena, Casiraghi, Nicola, Arrigoni, Alberto, Vanoni, Marco, Coccetti, Paola, De Gioia, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399832/
https://www.ncbi.nlm.nih.gov/pubmed/22815819
http://dx.doi.org/10.1371/journal.pone.0040786