Development of Elvitegravir Resistance and Linkage of Integrase Inhibitor Mutations with Protease and Reverse Transcriptase Resistance Mutations

Failure of antiretroviral regimens containing elvitegravir (EVG) and raltegravir (RAL) can result in the appearance of integrase inhibitor (INI) drug-resistance mutations (DRMs). While several INI DRMs have been identified, the evolution of EVG DRMs and the linkage of these DRMs with protease inhibi...

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Detalles Bibliográficos
Autores principales: Winters, Mark A., Lloyd, Robert M., Shafer, Robert W., Kozal, Michael J., Miller, Michael D., Holodniy, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399858/
https://www.ncbi.nlm.nih.gov/pubmed/22815755
http://dx.doi.org/10.1371/journal.pone.0040514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399858/
https://www.ncbi.nlm.nih.gov/pubmed/22815755
http://dx.doi.org/10.1371/journal.pone.0040514

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