Prenatal Treatment of Mosaic Mice (Atp7a mo-ms) Mouse Model for Menkes Disease, with Copper Combined by Dimethyldithiocarbamate (DMDTC)

Menkes disease is a fatal neurodegenerative disorder in infants caused by mutations in the gene ATP7A which encodes a copper (Cu) transporter. Defects in ATP7A lead to accumulated copper in the small intestine and kidneys and to copper deficiencies in the brain and the liver. The copper level in the...

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Detalles Bibliográficos
Autores principales: Lenartowicz, Małgorzata, Krzeptowski, Wojciech, Koteja, Paweł, Chrząścik, Katarzyna, Møller, Lisbeth Birk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399861/
https://www.ncbi.nlm.nih.gov/pubmed/22815746
http://dx.doi.org/10.1371/journal.pone.0040400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399861/
https://www.ncbi.nlm.nih.gov/pubmed/22815746
http://dx.doi.org/10.1371/journal.pone.0040400

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