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Epigenetic variation during the adult lifespan: cross-sectional and longitudinal data on monozygotic twin pairs

The accumulation of epigenetic changes was proposed to contribute to the age-related increase in the risk of most common diseases. In this study on 230 monozygotic twin pairs (MZ pairs), aged 18–89 years, we investigated the occurrence of epigenetic changes over the adult lifespan. Using mass spectr...

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Detalles Bibliográficos
Autores principales: Talens, Rudolf P, Christensen, Kaare, Putter, Hein, Willemsen, Gonneke, Christiansen, Lene, Kremer, Dennis, Suchiman, H Eka D, Slagboom, P Eline, Boomsma, Dorret I, Heijmans, Bastiaan T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399918/
https://www.ncbi.nlm.nih.gov/pubmed/22621408
http://dx.doi.org/10.1111/j.1474-9726.2012.00835.x