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The Molecular Dynamics of Trypanosoma brucei UDP-Galactose 4′-Epimerase: A Drug Target for African Sleeping Sickness

During the past century, several epidemics of human African trypanosomiasis, a deadly disease caused by the protist Trypanosoma brucei, have afflicted sub-Saharan Africa. Over 10 000 new victims are reported each year, with hundreds of thousands more at risk. As current drug treatments are either hi...

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Detalles Bibliográficos
Autores principales: Friedman, Aaron J, Durrant, Jacob D, Pierce, Levi C T, McCorvie, Thomas J, Timson, David J, McCammon, J Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399956/
https://www.ncbi.nlm.nih.gov/pubmed/22487100
http://dx.doi.org/10.1111/j.1747-0285.2012.01392.x