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MicroRNA-191 triggers keratinocytes senescence by SATB1 and CDK6 downregulation
Keratinocyte replicative senescence has an important role in time-dependent changes of the epidermis, a tissue with high turnover. Senescence encompasses growth arrest during which cells remain metabolically active but acquire a typical enlarged, vacuolar and flattened morphology. It is also accompa...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400053/ https://www.ncbi.nlm.nih.gov/pubmed/22683624 http://dx.doi.org/10.1016/j.bbrc.2012.05.153 |