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Impact of the NK Cell Receptor LIR-1 (ILT-2/CD85j/LILRB1) on Cytotoxicity against Multiple Myeloma

The role of different receptors in natural-killer- (NK-) cell-mediated cytotoxicity against multiple myeloma (MM) cells is unknown. We investigated if an enhancement of NK-cell-mediated cytotoxicity against MM could be reached by blocking of the inhibitory leukocyte immunoglobulin-like receptor 1 (L...

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Detalles Bibliográficos
Autores principales: Heidenreich, Silke, zu Eulenburg, Christine, Hildebrandt, York, Stübig, Thomas, Sierich, Heidi, Badbaran, Anita, Eiermann, Thomas H., Binder, Thomas M. C., Kröger, Nicolaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400434/
https://www.ncbi.nlm.nih.gov/pubmed/22844324
http://dx.doi.org/10.1155/2012/652130