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Reversal of PCNA Ubiquitylation by Ubp10 in Saccharomyces cerevisiae

Regulation of PCNA ubiquitylation plays a key role in the tolerance to DNA damage in eukaryotes. Although the evolutionary conserved mechanism of PCNA ubiquitylation is well understood, the deubiquitylation of ubPCNA remains poorly characterized. Here, we show that the histone H2B(K123) ubiquitin pr...

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Detalles Bibliográficos
Autores principales: Gallego-Sánchez, Alfonso, Andrés, Sonia, Conde, Francisco, San-Segundo, Pedro A., Bueno, Avelino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400564/
https://www.ncbi.nlm.nih.gov/pubmed/22829782
http://dx.doi.org/10.1371/journal.pgen.1002826