Downregulation of Polo-Like Kinase 4 in Hepatocellular Carcinoma Associates with Poor Prognosis

Polo-like kinase 4 (PLK4), belonging to serine/threonine kinase family, is critical for centriole replication and cell cycle progression. PLK4 has been proposed as a tumor suppressor in hepatocellular carcinoma (HCC). However, its expression and significance in HCC have not been well studied. In the...

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Detalles Bibliográficos
Autores principales: Liu, Lili, Zhang, Chris Zhiyi, Cai, Muyan, Fu, Jia, Chen, George Gong, Yun, Jingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400587/
https://www.ncbi.nlm.nih.gov/pubmed/22829937
http://dx.doi.org/10.1371/journal.pone.0041293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400587/
https://www.ncbi.nlm.nih.gov/pubmed/22829937
http://dx.doi.org/10.1371/journal.pone.0041293

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