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Downregulation of Polo-Like Kinase 4 in Hepatocellular Carcinoma Associates with Poor Prognosis
Polo-like kinase 4 (PLK4), belonging to serine/threonine kinase family, is critical for centriole replication and cell cycle progression. PLK4 has been proposed as a tumor suppressor in hepatocellular carcinoma (HCC). However, its expression and significance in HCC have not been well studied. In the...
Autores principales: | Liu, Lili, Zhang, Chris Zhiyi, Cai, Muyan, Fu, Jia, Chen, George Gong, Yun, Jingping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400587/ https://www.ncbi.nlm.nih.gov/pubmed/22829937 http://dx.doi.org/10.1371/journal.pone.0041293 |
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