Modular Design of Artificial Tissue Homeostasis: Robust Control through Synthetic Cellular Heterogeneity

Synthetic biology efforts have largely focused on small engineered gene networks, yet understanding how to integrate multiple synthetic modules and interface them with endogenous pathways remains a challenge. Here we present the design, system integration, and analysis of several large scale synthet...

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Detalles Bibliográficos
Autores principales: Miller, Miles, Hafner, Marc, Sontag, Eduardo, Davidsohn, Noah, Subramanian, Sairam, Purnick, Priscilla E. M., Lauffenburger, Douglas, Weiss, Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400602/
https://www.ncbi.nlm.nih.gov/pubmed/22829755
http://dx.doi.org/10.1371/journal.pcbi.1002579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400602/
https://www.ncbi.nlm.nih.gov/pubmed/22829755
http://dx.doi.org/10.1371/journal.pcbi.1002579

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