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Modular Design of Artificial Tissue Homeostasis: Robust Control through Synthetic Cellular Heterogeneity
Synthetic biology efforts have largely focused on small engineered gene networks, yet understanding how to integrate multiple synthetic modules and interface them with endogenous pathways remains a challenge. Here we present the design, system integration, and analysis of several large scale synthet...
Autores principales: | Miller, Miles, Hafner, Marc, Sontag, Eduardo, Davidsohn, Noah, Subramanian, Sairam, Purnick, Priscilla E. M., Lauffenburger, Douglas, Weiss, Ron |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400602/ https://www.ncbi.nlm.nih.gov/pubmed/22829755 http://dx.doi.org/10.1371/journal.pcbi.1002579 |
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