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Cofactor Binding Protects Flavodoxin against Oxidative Stress

In organisms, various protective mechanisms against oxidative damaging of proteins exist. Here, we show that cofactor binding is among these mechanisms, because flavin mononucleotide (FMN) protects Azotobacter vinelandii flavodoxin against hydrogen peroxide-induced oxidation. We identify an oxidatio...

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Detalles Bibliográficos
Autores principales: Lindhoud, Simon, van den Berg, Willy A. M., van den Heuvel, Robert H. H., Heck, Albert J. R., van Mierlo, Carlo P. M., van Berkel, Willem J. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400614/
https://www.ncbi.nlm.nih.gov/pubmed/22829943
http://dx.doi.org/10.1371/journal.pone.0041363