Cargando…
A Novel Source of Methylglyoxal and Glyoxal in Retina: Implications for Age-Related Macular Degeneration
Aging of retinal pigment epithelial (RPE) cells of the eye is marked by accumulations of bisretinoid fluorophores; two of the compounds within this lipofuscin mixture are A2E and all-trans-retinal dimer. These pigments are implicated in pathological mechanisms involved in some vision-threatening dis...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400616/ https://www.ncbi.nlm.nih.gov/pubmed/22829938 http://dx.doi.org/10.1371/journal.pone.0041309 |