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A Novel Source of Methylglyoxal and Glyoxal in Retina: Implications for Age-Related Macular Degeneration

Aging of retinal pigment epithelial (RPE) cells of the eye is marked by accumulations of bisretinoid fluorophores; two of the compounds within this lipofuscin mixture are A2E and all-trans-retinal dimer. These pigments are implicated in pathological mechanisms involved in some vision-threatening dis...

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Detalles Bibliográficos
Autores principales:	Yoon, Kee Dong, Yamamoto, Kazunori, Ueda, Keiko, Zhou, Jilin, Sparrow, Janet R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400616/ https://www.ncbi.nlm.nih.gov/pubmed/22829938 http://dx.doi.org/10.1371/journal.pone.0041309

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