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Comprehensive Identification and Annotation of Cell Type-Specific and Ubiquitous CTCF-Binding Sites in the Human Genome

Chromatin insulators are DNA elements that regulate the level of gene expression either by preventing gene silencing through the maintenance of heterochromatin boundaries or by preventing gene activation by blocking interactions between enhancers and promoters. CCCTC-binding factor (CTCF), a ubiquit...

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Detalles Bibliográficos
Autores principales: Chen, Hebing, Tian, Yao, Shu, Wenjie, Bo, Xiaochen, Wang, Shengqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400636/
https://www.ncbi.nlm.nih.gov/pubmed/22829947
http://dx.doi.org/10.1371/journal.pone.0041374